The fourth edition of Protective Groups in Organic Synthesis include updates on protective group chemistry from the years 1998 forward. In addition to incorporating any new protective groups now available to the synthetic organic chemist, the book also updates the old protective group content with new methodology discussing the installation and cleavage of protective groups. The fourth edition is comprehensive in the overall scope of coverage, and provides the most relevant and useful examples to illustrate each methodology. Protective Groups is a useful guide to the organic chemist, and the content is organized on the basis of the functional group to be protected (i.e., ethers, amides, phenols, phosphates, etc.). Within each section, the organization goes from the simple protective groups to the most complicated (in terms of structure).