Describing the processes in stars which produce the chemical elements for planets and life, this book shows how similar processes may be reproduced in laboratories using exotic beams, and how these results can be analyzed. Beginning with one-channel scattering theory, the book builds up to multi-channel reactions. Emphasis is placed on using transfer and breakup reactions to probe structure and predict capture processes, as well as R-matrix methods for modeling compound nucleus dynamics described by Hauser-Feshbach methods. Practical applications are prominent in this book, confronting theory predictions with data throughout. The associated reaction program Fresco is described, allowing readers to apply the methods to practical cases. Each chapter ends with exercises so readers can test their understanding of the materials covered.