Pharmacology's successful approach emphasises the mechanisms by which drugs act and relates these to the overall pharmacological effects and clinical uses. In doing so it sets out for the reader a clear route from a molecular understanding of receptors and drug actions, to the therapeutic uses of the most important groups of drugs. An especially well written textbook - it is regularly cited by students as the best textbook they have used. NOW WITH ACCESS TO FULL TEXT ONLINE PLUS MANY OTHER EXTRAS - POSTED ON STUDENTCONSULT.COM ACCESS IS VIA UNIQUE PIN NUMBER IN FRONT OF BOOK.Presented in full colour, with a new page format and design, the Fifth Edition has been fully updated, incorporating significant new information published in the last few years while dated or obsolete material has been removed. New agents are fully discussed as well as extensions of basic knowledge which presage further drug development.This book concentrates on explaining the mechanisms by which drugs act and relates these to their overall pharmacological effects and clinical uses. Clinical application summary boxes throughout reflect the book's increased emphasis on aspects of clinical pharmacology and the clinical use of drugs.An exceptionally well-written textbook for a major subject in every medical curriculum and also used for a large range of other science/health related courses.The clinical emphasis is appropriate for the changes in medical teaching providing the student with the necessary overview on how a class of drugs will be used in a clinical situation. Clinical application summary boxes throughout reflect the book's increased emphasis on aspects of clinical pharmacology and the clinical use of drugs. Puts pharmacology in the perspective of the other science subjects, especially physiology and biochemistry. Most chapters have brief summaries of relevant physiological and biochemical processes at the beginning to form a basis for the subsequent treatment of pharmacological actions."Key points boxes" included in each chapter highlighting all the main facts and ideas.Appendix lists the most important pharmacological agents divided into those of primary and secondary interest.Annotated reference and further reading lists are included with emphasis on recent reviews and papers covering significant new advances.Page size increased to a larger format to allow enhanced presentation of text features and a more open layoutIn full colour throughout with all the line diagrams now in full colour to enhance presentation and understanding of their content. Chapter overviews introduced to the start of all chapters to help the readerNew 'small print' sections included in many chapters. These contain mainly complex, sometimes speculative, material, which can be skipped by the reader in a hurry without losing the main thread, but will be of interest to readers wishing to go into greater depth. A new introductory chapter on What is Pharmacology?New chapters on cellular pharmacology - Excitation, contraction and secretion and Cell proliferation and apoptosis - which describe the cellular mechanisms that are affected by many important drugs described in later parts of the book.A revision and re-organisation of the chemotherapy section which is now called Drugs used in the treatment of infections and cancer.One new chapter in the final section on Drug discovery looks at the rapidly changing processes involved which are driven by advances in molecular biology. It contains a brief account of the regulatory controls involved.