The carefully revised Third Edition features expanded clinical coverage, new "Apply Your Knowledge" critical thinking questions, and a new flowchart style that makes it easier than ever for students to focus on key physiological processes. Features such as Chemistry Review boxes provide additional resources for students who need them, while Toolboxes and Discovery boxes allow instructors the option of delving into more detail about physiology topics. Every new copy of the book now includes the InterActive Physiology® 9-System Suite CD-ROM, which features a new module on the digestive system, as well as access to an expanded The Physiology Place website and PhysioEx®7.0 online laboratory simulations. Clinical Connections boxes focus on clinical topics to help students apply the physiology they've learned to conditions such as cancer, cystic fibrosis, and diabetes Discovery boxes focus on chapter-related topics in more depth. Examples include coverage of creatine supplements, the effects of high altitude, and why we can't drink seawater. Toolboxes and Chemistry Review boxes review or introduce concepts from math, physics, and chemistry and show how they apply to physiology. By presenting this content in a way that doesn't interfere with the flow of the text, these boxes give instructors the flexibility to tailor the text for students with a wide variety of backgrounds. Examples of topics include the Nernst Equation, Fick's Law, Laplace's Law, and ions and ionic bonds. Gorgeous, pedagogically-oriented art uses consistent colors and icons to reinforce student learning. Selected figures in each chapter appear with figure-questions to reinforce learning. Consistent integration of physiology material helps students tie concepts together through three features: Systems Integration charts provide dynamic, one-page summaries that explain and give examples of how a given organ system affects other systems discussed in the book. Exercise Links, using a consistent story about two characters running a marathon, present physiology as an integrated whole by discussing the relevance of specific topics to exercise and. Chapter 24, The Whole Body: Integrated Physiology Responses to Exercise discusses how exercise affects virtually all aspects of body function.